Evidence-based harm reduction
The evidence on psychoactive substances,
organized and cited
The information exists — scattered across journals, forums, and paywalls. We organized it: compound profiles that pair effects with risks, clinical research linked to source, and harm reduction that's never an afterthought.
- 23
- compounds
- 266
- clinical studies
- 46
- research PDFs
- 51
- interaction rules
Start with a compound
Psilocybin
Naturally occurring psychedelic compound found in certain mushroom species. Psilocybin is converted…
PsychedelicLSD
Semisynthetic psychedelic derived from ergot alkaloids. One of the most potent psychedelics known, w…
PsychedelicMDMA
Empathogenic stimulant known for producing feelings of euphoria, emotional warmth, and enhanced empa…
EmpathogenKetamine
Dissociative anesthetic used medically and recreationally. Known for inducing the 'K-hole' at higher…
DissociativeN,N-DMT
Powerful, short-acting psychedelic tryptamine found in many plants and animals. Produces intense vis…
PsychedelicTHC
Primary psychoactive compound in cannabis. Produces euphoria, relaxation, and altered sensory percep…
CannabinoidGo deeper
Clinical research
266 peer-reviewed studies with summaries and DOI links.
Books
38 essential reads across science, memoir, and practice.
Films
18 documentaries worth your evening.
Podcasts
16 shows on research, therapy, and policy.
Music
Playlists organized by intention — preparation to integration.
Principles
Science over stigma
Clinical language where accuracy demands it, plain language everywhere else. No scare tactics, no glamour — the data speaks.
Harm reduction first
Risks sit beside effects. Dosage comes with context. Interactions are front and center, and crisis support is one tap away.
Cite everything
Claims require sources. "Trust us" is never the answer — "here's the study" is.